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PRESENTED BY NOTION |
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Happy Thursday, Future Party. We want to get to know you better, so we have a favor to ask. Take our survey to tell us what you love about us and what we can improve in the future. And because we know your time is valuable, we’re throwing in a chance to win a $50 gift card. Enter here. |
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The Zuckerbergs Want To Understand You On A Cellular Level |
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Generating biology // Illustration by Kate Walker |
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Mark Zuckerberg and Priscilla Chan’s research nonprofit, Biohub, has enlisted Google and the federal government to create a “universal virtual cell.” |
Why It Hits: Biohub is now almost solely dedicated to eradicating disease, which means it needs to understand how the human body works at a truly cellular level. The nonprofit believes AI could make that ambition a reality. It just needs a lot of money and data to make its systems useful enough. |
Between The Cells: Biohub wants to bring biological experiments into the digital realm. |
The nonprofit is partnering with Meta, Google DeepMind, Isomorphic Labs, the Department of Energy, and the National Institutes of Health to organize $1.8 billion in funding, data, computing, and measurement technology, per Axios. The plan is to use those resources to create a universal virtual cell that accurately reflects how a real cell would behave in the human body. Partner companies will get exclusive one-year access to Biohub’s data before it’s open-sourced to the wider medical and research community.
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Under The Microscope: Biology is one of the hardest sciences for AI to explore because it requires so much real-world empirical data to train models. But the effort is worth it because the potential upside could make it one of AI’s greatest use cases. |
Scientists around the world could perform virtual experiments on the digital cell, saving millions of dollars in lab work and speeding up medical breakthroughs. Down the line, the system could be used to model individual people’s cellular makeup to better understand their medical issues or develop medicines and therapies tailored to their specific needs. |
The Future: It wouldn’t be surprising if Meta and Google eventually launch pharmaceutical arms focused on longevity therapies or cognitive supplements based on Biohub’s breakthroughs. |
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Together with Notion |
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Your Notion Workspace Is A Product. Start Treating It Like One. |
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Early-stage teams move quickly, but their internal systems often struggle to keep up. |
In the first few months of building a company, it’s easy for documentation, roadmaps, meeting notes, hiring plans, and customer insights to get scattered across different tools and conversations. |
At first, that mess feels manageable. But as the team grows, every unclear process becomes a drag on execution. |
The most effective founders treat their workspace like a product. That means designing it intentionally, with a clear structure, useful templates, shared naming conventions, and a simple onboarding experience for every new team member. |
A strong workspace should make work easier to find, decisions easier to track, and priorities easier to understand. |
Operational debt compounds just like technical debt. Every duplicate doc, lost decision, or unclear handoff slows the team down. |
By building a clean, scalable workspace early, founders create a stronger foundation for faster execution, better collaboration, and less time wasted searching for context. |
Build a workspace that scales with your team. |
Try Notion today and get up to 3 months free of Notion Business with Notion AI. |
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Nextdoor Wants The Most Targeted Ads |
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Big Buck Boulevard // Illustration by Kate Walker |
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Local-community-focused social platform Nextdoor is making a big play for advertising dominance by focusing on geographics instead of demographics. |
The Big Pitch: Nextdoor’s ad business is still a long way from competing with larger platforms like Meta, TikTok, and X. But the division is growing, with revenue increasing 15% to $75 million last quarter. By leaning into what Nextdoor already does best — connecting neighbors — the company hopes to carve out an important niche in the market. |
Between The Lawns: Nextdoor is monetizing the neighborhood. |
Its new tool, “Neighborhood Intelligence,” has mapped 350,000 individual neighborhoods across the US to create a “neighborhood graph.” According to Insider, marketers can use the graph to see how people in different neighborhoods are talking about their brands. That allows brands to “target specific geographies with ads on Nextdoor that speak directly to those conversations.” Several blue-chip companies, including Pepsi, are already exploring the tool.
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Last Looks: Nextdoor CEO Nirav Tolia told Insider that the ability to tailor marketing to specific neighborhoods is especially powerful for businesses with inconsistent sales across regions, such as restaurant chains or car dealerships. It could also allow brands to analyze how certain neighborhoods have strikingly similar or wildly different purchasing patterns. |
Ultimately, Neighborhood Intelligence is a bet that where people live IRL is the best way to reach them digitally. |
Prediction: Nextdoor could prove especially useful for launching small, location-based businesses. After all, there’s no better customer than someone who lives down the street. |
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Together with The GIST |
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The GIST Keeps You In The Know |
Don’t have time to catch all of your favorite team’s games? Struggling to keep up with the flood of sports news? You’re not alone. |
With so much content, staying in the know can be hard. That’s where The GIST comes in. |
The GIST’s free, 4x-weekly newsletter keeps you up-to-date on the best sports and pop culture moments, all in less than 5 minutes. |
Subscribe today, know all the things tomorrow. |
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DEEP DIVES |
Read: Variety sits down with Ben Affleck to discuss his next directorial effort, Animals, and the expansion of Artists Equity, which he co-founded with Matt Damon. Listen: Decoder chats with California Senator Adam Schiff about the ins and outs of tech regulation. Watch: Quantum Marketing talks with Airbnb Chief Experience Officer Hiroki Asai about why the brand is investing so heavily in the local-experiences economy.
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Do you use Nextdoor? |
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35.5% of you voted They’ve gotten too expensive in yesterday’s poll: How do you feel about spending money at leisure-economy brands like Dave & Buster’s, Lucky Strike, or Six Flags? |
“I’m surprised by this metric because whenever I go to D&B, the place is packed!” |
“D&B has been a go-to for me for many years, but they’ve changed their business model and increased prices, so it’s not as fun or worth the expense anymore.” |
“Like professional sports, they’re pricing out us regular folks.” |
“I go to D&B at least once a month.” |
“My partner and I bought our first Six Flags season passes this year and already renewed for next year with Fast Lane! It’s expensive, but so much fun and a great deal compared to daily tickets. Just bring your own food!” |
Let’s keep the conversation going. Join Poll Of The Day, so your opinions can shine. Discover how your views line up with your peers’, check out cool insights, and have some fun. It’s data with personality. |
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Let us know how we are doing... |
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PARTNERSHIPS | COMMUNITY | PODCAST | FRIENDS |
Today’s email was written by David Vendrell.
Edited by Nick Comney. Polled and Copy-edited by Kait Cunniff.
Published by Darline Salazar. |
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